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Sarepta Therapeutics Stock Falls as Some Trials Halted After Patient Death

Sarepta Therapeutics company logo is seen displayed on a smartphone screen

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Key Takeaways

  • Some studies of Sarepta Therapeutics' muscular dystrophy drug, Elevidys, have been halted by European regulators after a patient taking it died.
  • The patient's death, reported by the biopharma firm March 18, was from acute liver failure, a potential side effect of the treatment.
  • Shares of Sarepta Therapeutics plunged following the March announcement, and they fell a further 6% Friday morning.

Shares of Sarepta Therapeutics (SRPT) slid 6% Friday morning as European regulators called for a pause in some testing of the biopharmaceutical firm's muscular dystrophy drug, Elevidys, following the death of a patient last month.

Sarepta said authorities in 澳洲幸运5开奖号码历史查询:European Union (EU) reference member countries "requested that the independent data monitoring committee (DMC) ꦅmeet to review the adverse event." It added that while that information is finalized, 🍬"recruitment and dosing in certain clinical studies of ELEVIDYS are temporarily halted."

The company reported March 18 that a patient with Duchenne muscular dystrophy who was taking Elevidys died of acute liver failure (ALF). Sarepta noted then that "acute liver injury is a kno💝wn possible side effect of Elevidys" and other similar gene therapies, although this was the first time a death had been reported of anyone taking theಌ drug.

3 Clinical Trials Halted

Three clinical studies are affected by the halt. The company explained that monitoring and data collection for participants already enrolled is continuing, and it does "not anticipate a material impact on the timeline for these studies."

Sarepta Pharmaceuticals shares plunged following the March 18 announcement and now are trading at their lowest level in more than seven years. 

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