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Moderna-Merck Vaccine for Skin Cancer Shows Positive Results; Moderna Stock Jumps

Moderna headquarters in Cambridge, Massachusetts.

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Key Takeaways

  • A vaccine made by Moderna and Merck showed promise in preventing recurrence and death for patients afflicted by skin cancer.
  • The Phase 2b trial indicated a reduced risk in recurrence and death in patients with stage III/IV melanoma compared to taking Merck's Keytruda cancer drug alone.
  • The personalized vaccine uses Moderna's breakthrough mRNA technology that was behind the company's COVID-19 shots.
  • Moderna shares were sharply higher, while Merck shares were down slightly following the news.

A personalized vaccine developed by Moderna (MRNA) and Merck (MRK) showed significant positive results 🔯in treating skin cancer in high risk patients.

The companies indicated the shot, which worked in combination with Merck’s Keytruda cancer drug, demonstrated in a Phase 2b trial “a clinically meaningful improvement in recurrence-free survival (RFS), reducing the risk of recurrence or death by 49%,” as compared to taking Keytruda alone. The research covered three years involving those with stage III/IV melanoma. 

The treatment involves analyzing the genetic makeup of each patient’s tumor so🧸 their immune system can recognize markers of abnorma🤡l growth.

Dr. Kyle ಌHolen, senior vice president and head of Development, Therapeutics, and Oncology at Moderna, said “we are excited to see such a robust clinical benefit” from the vaccine.

Moderna has been seeking new uses for its mRNA technology, which was key in creating the company's COVID-19 shots.

The two drug makers have already initiated a Phase 3 study of the🅷 therapy.

Moderna shares were up 9.5% at $86.10 at 1:30 p.m. ET, while Merck shares were down 1.2% at $105.80.

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